Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human)) | BDBM243059 (PTP inhibitor, 4k) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.82E+3 | n/a | n/a | n/a | n/a | 6.5 | 30 |
Yanbian University College of Pharmacy | Assay Description Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g... | J Enzyme Inhib Med Chem 28: 1199-204 (2013) Article DOI: 10.3109/14756366.2012.723206 BindingDB Entry DOI: 10.7270/Q2668C3G | |||||||||||
More data for this Ligand-Target Pair |