Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 1' and Ligand = 'BDBM325236'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325236 (2-(2-isopropylpyridin-3- | US10189841, Compound I-...) Show SMILES CC(C)c1ncccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3ccc(n3)C3CCN(C)CC3)c2n1 Show InChI InChI=1S/C29H32N8O/c1-19(2)26-23(5-4-13-30-26)27-31-17-25-28(33-27)36(29(38)32-25)18-20-6-8-22(9-7-20)37-16-12-24(34-37)21-10-14-35(3)15-11-21/h4-9,12-13,16-17,19,21H,10-11,14-15,18H2,1-3H3,(H,32,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325236 (2-(2-isopropylpyridin-3- | US10189841, Compound I-...) Show SMILES CC(C)c1ncccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3ccc(n3)C3CCN(C)CC3)c2n1 Show InChI InChI=1S/C29H32N8O/c1-19(2)26-23(5-4-13-30-26)27-31-17-25-28(33-27)36(29(38)32-25)18-20-6-8-22(9-7-20)37-16-12-24(34-37)21-10-14-35(3)15-11-21/h4-9,12-13,16-17,19,21H,10-11,14-15,18H2,1-3H3,(H,32,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair