Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 1' and Ligand = 'BDBM325243'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325243 (2-(2-isopropylphenyl)-7- | US10189841, Compound I-...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(CC3CCN(CC3)S(=O)(=O)c3cccnc3)c2n1 Show InChI InChI=1S/C26H30N6O3S/c1-18(2)21-8-4-5-9-22(21)24-28-16-23-25(29-24)32(26(33)30(23)3)17-19-10-13-31(14-11-19)36(34,35)20-7-6-12-27-15-20/h4-9,12,15-16,18-19H,10-11,13-14,17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325243 (2-(2-isopropylphenyl)-7- | US10189841, Compound I-...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(CC3CCN(CC3)S(=O)(=O)c3cccnc3)c2n1 Show InChI InChI=1S/C26H30N6O3S/c1-18(2)21-8-4-5-9-22(21)24-28-16-23-25(29-24)32(26(33)30(23)3)17-19-10-13-31(14-11-19)36(34,35)20-7-6-12-27-15-20/h4-9,12,15-16,18-19H,10-11,13-14,17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				Citation and Details BindingDB Entry DOI: 10.7270/Q2TH8QWM
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325243 (2-(2-isopropylphenyl)-7- | US10189841, Compound I-...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(CC3CCN(CC3)S(=O)(=O)c3cccnc3)c2n1 Show InChI InChI=1S/C26H30N6O3S/c1-18(2)21-8-4-5-9-22(21)24-28-16-23-25(29-24)32(26(33)30(23)3)17-19-10-13-31(14-11-19)36(34,35)20-7-6-12-27-15-20/h4-9,12,15-16,18-19H,10-11,13-14,17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair