Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 1' and Ligand = 'BDBM325256'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325256 (9-((1- | US10189841, Compound I-462 | US10399980, ...) Show SMILES CC(C)C(=O)N1CCC(Cn2c3nc(ncc3n(C)c2=O)-c2ccccc2C(C)C)CC1 Show InChI InChI=1S/C25H33N5O2/c1-16(2)19-8-6-7-9-20(19)22-26-14-21-23(27-22)30(25(32)28(21)5)15-18-10-12-29(13-11-18)24(31)17(3)4/h6-9,14,16-18H,10-13,15H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325256 (9-((1- | US10189841, Compound I-462 | US10399980, ...) Show SMILES CC(C)C(=O)N1CCC(Cn2c3nc(ncc3n(C)c2=O)-c2ccccc2C(C)C)CC1 Show InChI InChI=1S/C25H33N5O2/c1-16(2)19-8-6-7-9-20(19)22-26-14-21-23(27-22)30(25(32)28(21)5)15-18-10-12-29(13-11-18)24(31)17(3)4/h6-9,14,16-18H,10-13,15H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				Citation and Details BindingDB Entry DOI: 10.7270/Q2TH8QWM
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325256 (9-((1- | US10189841, Compound I-462 | US10399980, ...) Show SMILES CC(C)C(=O)N1CCC(Cn2c3nc(ncc3n(C)c2=O)-c2ccccc2C(C)C)CC1 Show InChI InChI=1S/C25H33N5O2/c1-16(2)19-8-6-7-9-20(19)22-26-14-21-23(27-22)30(25(32)28(21)5)15-18-10-12-29(13-11-18)24(31)17(3)4/h6-9,14,16-18H,10-13,15H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10399980 (2019) BindingDB Entry DOI: 10.7270/Q23J3GCX
					More data for this Ligand-Target Pair