Found 3 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 7' and Ligand = 'BDBM50393445' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Ubiquitin carboxyl-terminal hydrolase 7
(Homo sapiens (Human)) | BDBM50393445
(CHEMBL2159504)Show SMILES COc1ccc(NC(=O)c2cc(c(Sc3c(Cl)cncc3Cl)s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C17H11Cl2N3O4S2/c1-26-10-4-2-9(3-5-10)21-16(23)14-6-13(22(24)25)17(27-14)28-15-11(18)7-20-8-12(15)19/h2-8H,1H3,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 7
(Homo sapiens (Human)) | BDBM50393445
(CHEMBL2159504)Show SMILES COc1ccc(NC(=O)c2cc(c(Sc3c(Cl)cncc3Cl)s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C17H11Cl2N3O4S2/c1-26-10-4-2-9(3-5-10)21-16(23)14-6-13(22(24)25)17(27-14)28-15-11(18)7-20-8-12(15)19/h2-8H,1H3,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | n/a | n/a | 430 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 7
(Homo sapiens (Human)) | BDBM50393445
(CHEMBL2159504)Show SMILES COc1ccc(NC(=O)c2cc(c(Sc3c(Cl)cncc3Cl)s2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C17H11Cl2N3O4S2/c1-26-10-4-2-9(3-5-10)21-16(23)14-6-13(22(24)25)17(27-14)28-15-11(18)7-20-8-12(15)19/h2-8H,1H3,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 430 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assay |
ACS Med Chem Lett 3: 789-792 (2012)
Article DOI: 10.1021/ml200276j
BindingDB Entry DOI: 10.7270/Q2154J51 |
More data for this
Ligand-Target Pair | |
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