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Found 1 hit Enz. Inhib. hit(s) with Target = 'Uridine phosphorylase 1' and Ligand = 'BDBM50030981'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Uridine phosphorylase 1


(Mus musculus)
BDBM50030981
PNG
(5-(3,5-Difluoro-benzyl)-1-(2-hydroxy-ethoxymethyl)...)
Show SMILES OCCOCn1cc(Cc2cc(F)cc(F)c2)c(=O)[nH]c1=O
Show InChI InChI=1S/C14H14F2N2O4/c15-11-4-9(5-12(16)6-11)3-10-7-18(8-22-2-1-19)14(21)17-13(10)20/h4-7,19H,1-3,8H2,(H,17,20,21)
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PC cid
PC sid
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Patents


Similars

PubMed
n/an/a 350n/an/an/an/an/an/a



Burroughs Wellcome Co.

Curated by ChEMBL


Assay Description
Inhibition of uridine phosphorylase (UrdPase) from murine liver.


J Med Chem 38: 3850-6 (1995)


BindingDB Entry DOI: 10.7270/Q2B27T91
More data for this
Ligand-Target Pair