Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Urokinase-type plasminogen activator' and Ligand = 'BDBM50009201'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50009201 (CHEMBL3238375) Show SMILES COc1ccc(Oc2ccc(cc2)N2CC(=O)N(Cc3cc4cnc(nc4n3C)C(=O)N[C@@H](CCCCN)C#N)C2=O)cc1 |r| Show InChI InChI=1S/C31H32N8O5/c1-37-23(15-20-17-34-28(36-29(20)37)30(41)35-21(16-33)5-3-4-14-32)18-39-27(40)19-38(31(39)42)22-6-8-25(9-7-22)44-26-12-10-24(43-2)11-13-26/h6-13,15,17,21H,3-5,14,18-19,32H2,1-2H3,(H,35,41)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hiroshima International University Curated by ChEMBL					Assay Description Inhibition of human plasma urokinase using Glu-Gly-Arg-pNA (S-2444) peptide as substrate assessed as reduction of enzyme hydrolytic activity				Bioorg Med Chem 22: 2339-52 (2014) Article DOI: 10.1016/j.bmc.2014.02.002 BindingDB Entry DOI: 10.7270/Q2KH0PVJ
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