new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Urotensin II receptor' and Ligand = 'BDBM50413776'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urotensin II receptor


(Homo sapiens (Human))
BDBM50413776
PNG
(CHEMBL505288)
Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC(C)(C)[C@@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r|
Show InChI InChI=1S/C53H73N11O10S2/c1-30(2)43(52(73)74)63-50(71)42-29-75-76-53(3,4)44(64-45(66)36(56)16-10-11-23-54)51(72)61-40(25-31-13-6-5-7-14-31)47(68)60-41(27-33-28-57-37-17-9-8-15-35(33)37)49(70)58-38(18-12-24-55)46(67)59-39(48(69)62-42)26-32-19-21-34(65)22-20-32/h5-9,13-15,17,19-22,28,30,36,38-44,57,65H,10-12,16,18,23-27,29,54-56H2,1-4H3,(H,58,70)(H,59,67)(H,60,68)(H,61,72)(H,62,69)(H,63,71)(H,64,66)(H,73,74)/t36-,38-,39-,40-,41+,42-,43-,44-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
219n/an/an/an/an/an/an/an/a



University of Naples Federico II

Curated by ChEMBL


Assay Description
Displacement of [125I]urotensin-2 from human UT2 receptor expressed in CHO-K1 cells by liquid scintillation counting


J Med Chem 52: 3927-40 (2009)


Article DOI: 10.1021/jm900148c
BindingDB Entry DOI: 10.7270/Q27W6DFT
More data for this
Ligand-Target Pair