Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 1' and Ligand = 'BDBM4859'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM4859 (1-(4-Chloroanilino)-4-[2,6-dimethylpyridin-4-ylmet...) Show SMILES Cc1cc(Cc2nnc(Nc3ccc(Cl)cc3)c3ccccc23)cc(C)n1 Show InChI InChI=1S/C22H19ClN4/c1-14-11-16(12-15(2)24-14)13-21-19-5-3-4-6-20(19)22(27-26-21)25-18-9-7-17(23)8-10-18/h3-12H,13H2,1-2H3,(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	22
Novartis Pharmaceuticals					Assay Description The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...				J Med Chem 43: 2310-23 (2000) Article DOI: 10.1021/jm9909443 BindingDB Entry DOI: 10.7270/Q24M92R5
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