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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 1' and Ligand = 'BDBM50065284'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 1


(Mus musculus)
BDBM50065284
PNG
(3-[1-(4-Chloro-1H-pyrazol-3-yl)-meth-(Z)-ylidene]-...)
Show SMILES Clc1cn[nH]c1C=C1C(=O)Nc2ccccc12 |w:6.6|
Show InChI InChI=1S/C12H8ClN3O/c13-9-6-14-16-11(9)5-8-7-3-1-2-4-10(7)15-12(8)17/h1-6H,(H,14,16)(H,15,17)
PDB
MMDB

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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.41E+3n/an/an/an/an/an/a



SUGEN, Inc.

Curated by ChEMBL


Assay Description
Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).


J Med Chem 41: 2588-603 (1998)


Article DOI: 10.1021/jm980123i
BindingDB Entry DOI: 10.7270/Q2G73CTT
More data for this
Ligand-Target Pair