Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM17697 (2-aminobenzoxazole, 22 | 4-({2-[(4-chloro-3-{[(2S)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 2.80 | -48.3 | 4.60 | n/a | n/a | n/a | n/a | 7.5 | 22 |
Amgen | Assay Description The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all... | J Med Chem 50: 4351-4373 (2007) Article DOI: 10.1021/jm070034i BindingDB Entry DOI: 10.7270/Q21V5C74 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |