Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM21074'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM21074 ((2E)-N-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-3-[...) Show SMILES Nc1noc2cccc(-c3ccc(NC(=O)\C=C\c4cccc(c4)C(F)(F)F)cc3)c12 Show InChI InChI=1S/C23H16F3N3O2/c24-23(25,26)16-4-1-3-14(13-16)7-12-20(30)28-17-10-8-15(9-11-17)18-5-2-6-19-21(18)22(27)29-31-19/h1-13H,(H2,27,29)(H,28,30)/b12-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				J Med Chem 51: 1231-41 (2008) Article DOI: 10.1021/jm701096v BindingDB Entry DOI: 10.7270/Q2HX19Z7
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