Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM227934'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM227934 (US10047096, 195 | trans-3-[({4-[(2-Fluoro-5-hydrox...) Show SMILES Cc1cc(F)c(Nc2ccnc3Nc4ccc(CN[C@H]5C[C@@H](C5)C(O)=O)cc4NC(=O)c23)cc1O |r,wU:19.18,wD:21.23,(-10.32,3.64,;-8.99,2.87,;-8.99,1.33,;-7.65,.56,;-7.65,-.98,;-6.32,1.33,;-4.99,.56,;-4.99,-.98,;-6.32,-1.75,;-6.32,-3.29,;-4.99,-4.06,;-3.65,-3.29,;-2.45,-4.25,;-.95,-3.91,;-.08,-5.18,;1.46,-5.07,;2.12,-3.68,;3.66,-3.68,;4.43,-2.34,;5.77,-1.57,;6.17,-.09,;7.65,-.48,;7.26,-1.97,;8.99,.29,;8.99,1.83,;10.32,-.48,;1.26,-2.41,;-.28,-2.52,;-.95,-1.13,;-2.45,-.79,;-2.85,.7,;-3.65,-1.75,;-6.32,2.87,;-7.65,3.64,;-7.65,5.18,)| Show InChI InChI=1S/C25H24FN5O4/c1-12-6-16(26)19(10-21(12)32)29-18-4-5-27-23-22(18)24(33)31-20-7-13(2-3-17(20)30-23)11-28-15-8-14(9-15)25(34)35/h2-7,10,14-15,28,32H,8-9,11H2,1H3,(H,31,33)(H,34,35)(H2,27,29,30)/t14-,15-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.573	n/a	n/a	n/a	n/a	7.0	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human KDR (amino acids D807-V1356), expresse...				US Patent US10047096 (2018) BindingDB Entry DOI: 10.7270/Q23R0VW4
					More data for this Ligand-Target Pair