Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM235826'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM235826 (US9364459, N) Show SMILES COc1cc(cc(OC)c1OC)C1=C(C(=O)NC1=O)c1cn(CCC[NH+]2CC[NH+](C)CC2)c2ccccc12 |t:13,(1.93,-1.66,;3.42,-1.27,;3.82,.22,;2.73,1.31,;3.13,2.8,;4.61,3.2,;5.7,2.11,;7.19,2.51,;7.59,3.99,;5.3,.62,;6.39,-.47,;7.88,-.07,;2.36,4.13,;.82,4.13,;.34,5.6,;-.99,6.37,;1.59,6.5,;2.83,5.6,;4.17,6.37,;.05,2.8,;.52,1.33,;-.72,.43,;-.72,-1.11,;-2.06,-1.88,;-2.06,-3.42,;-3.39,-4.19,;-4.73,-3.42,;-6.06,-4.19,;-6.06,-5.73,;-7.88,-6.5,;-4.73,-6.5,;-3.39,-5.73,;-1.97,1.33,;-3.48,1.01,;-4.51,2.16,;-4.03,3.62,;-2.52,3.94,;-1.49,2.8,)| Show InChI InChI=1S/C29H34N4O5/c1-31-12-14-32(15-13-31)10-7-11-33-18-21(20-8-5-6-9-22(20)33)26-25(28(34)30-29(26)35)19-16-23(36-2)27(38-4)24(17-19)37-3/h5-6,8-9,16-18H,7,10-15H2,1-4H3,(H,30,34,35)/p+2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-Universität Mainz; Universitätsmedizin der Johannes Gutenberg-Universität Mainz US Patent					Assay Description The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...				US Patent US9364459 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5FK2
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