Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50162157 (1-[4-(6,7-Dimethoxy-quinazolin-4-yloxy)-phenyl]-3-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Kirin Brewery Co. Ltd. Curated by ChEMBL | Assay Description Inhibition of vascular endothelial growth factor receptor 2 | J Med Chem 48: 1359-66 (2005) Article DOI: 10.1021/jm030427r BindingDB Entry DOI: 10.7270/Q23J3CG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50162157 (1-[4-(6,7-Dimethoxy-quinazolin-4-yloxy)-phenyl]-3-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Univ Lille Nord de France, F-59000 Lille, France; UDSL, ICPAL, EA 4481, F-59006 Lille, France. Curated by ChEMBL | Assay Description Inhibition of KDR | Bioorg Med Chem Lett 21: 2106-12 (2011) Article DOI: 10.1016/j.bmcl.2011.01.137 BindingDB Entry DOI: 10.7270/Q2C24WRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50162157 (1-[4-(6,7-Dimethoxy-quinazolin-4-yloxy)-phenyl]-3-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Lille Nord de France Curated by ChEMBL | Assay Description Inhibition of recombinant human VEGFR-2 using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation counting | J Med Chem 55: 1189-204 (2012) Article DOI: 10.1021/jm2013453 BindingDB Entry DOI: 10.7270/Q2086695 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50162157 (1-[4-(6,7-Dimethoxy-quinazolin-4-yloxy)-phenyl]-3-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Univ Lille Nord de France, F-59000 Lille, France; UDSL, ICPAL, EA 4481, F-59006 Lille, France. Curated by ChEMBL | Assay Description Inhibition of recombinant human VEGFR-2-mediated poly(Glu4Tyr) phosphorylation after 1 hr | Bioorg Med Chem Lett 21: 2106-12 (2011) Article DOI: 10.1016/j.bmcl.2011.01.137 BindingDB Entry DOI: 10.7270/Q2C24WRV | |||||||||||
More data for this Ligand-Target Pair |