Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50185172 (2-(6-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science& Technology Curated by ChEMBL | Assay Description Inhibition of recombinant human VEGFR2 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA | J Med Chem 59: 6690-708 (2016) Article DOI: 10.1021/acs.jmedchem.6b00056 BindingDB Entry DOI: 10.7270/Q2474CT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Mus musculus) | BDBM50185172 (2-(6-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation Curated by ChEMBL | Assay Description Inhibition of VEGFR2 | Bioorg Med Chem Lett 16: 3595-9 (2006) Article DOI: 10.1016/j.bmcl.2006.03.069 BindingDB Entry DOI: 10.7270/Q2BZ65N7 | |||||||||||
More data for this Ligand-Target Pair |