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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50185177'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM50185177
PNG
(2-(1H-indazol-3-yl)-N-methyl-N-(1-methylpiperidin-...)
Show SMILES CN(C1CCN(C)CC1)c1ccc2nc([nH]c2c1)-c1n[nH]c2ccccc12
Show InChI InChI=1S/C21H24N6/c1-26-11-9-14(10-12-26)27(2)15-7-8-18-19(13-15)23-21(22-18)20-16-5-3-4-6-17(16)24-25-20/h3-8,13-14H,9-12H2,1-2H3,(H,22,23)(H,24,25)
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Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Chiron Corporation

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2


Bioorg Med Chem Lett 16: 3595-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.069
BindingDB Entry DOI: 10.7270/Q2BZ65N7
More data for this
Ligand-Target Pair