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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)' and Ligand = 'BDBM4910'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM4910
PNG
((3Z)-6-(3-methoxyphenyl)-3-(4,5,6,7-tetrahydro-1H-...)
Show SMILES COc1cccc(c1)-c1ccc2\C(=C\c3cc4CCCCc4[nH]3)C(=O)Nc2c1
Show InChI InChI=1S/C24H22N2O2/c1-28-19-7-4-6-15(12-19)16-9-10-20-21(24(27)26-23(20)13-16)14-18-11-17-5-2-3-8-22(17)25-18/h4,6-7,9-14,25H,2-3,5,8H2,1H3,(H,26,27)/b21-14-
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.00E+4n/an/an/an/a7.522



SUGEN, Inc.



Assay Description
The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...


J Med Chem 43: 2655-63 (2000)


Article DOI: 10.1074/jbc.M512374200
BindingDB Entry DOI: 10.7270/Q2W66J0N
More data for this
Ligand-Target Pair