new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)' and Ligand = 'BDBM50126845'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50126845
PNG
(CHEMBL3628814)
Show SMILES COc1ccc(Nc2ncc3CSc4cc(OC)ccc4-c3n2)cc1
Show InChI InChI=1S/C19H17N3O2S/c1-23-14-5-3-13(4-6-14)21-19-20-10-12-11-25-17-9-15(24-2)7-8-16(17)18(12)22-19/h3-10H,11H2,1-2H3,(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.75E+4n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assay


Eur J Med Chem 103: 29-43 (2015)


BindingDB Entry DOI: 10.7270/Q2G162MG
More data for this
Ligand-Target Pair