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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vasopressin V1a receptor' and Ligand = 'BDBM50354911'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vasopressin V1a receptor


(Homo sapiens (Human))		BDBM50354911
PNG
(CHEMBL1837016)
Show SMILES Cc1nnc(C2CCN(CC2)c2ccccn2)n1-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H20F3N5/c1-14-25-26-19(28(14)17-7-5-16(6-8-17)20(21,22)23)15-9-12-27(13-10-15)18-4-2-3-11-24-18/h2-8,11,15H,9-10,12-13H2,1H3
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PC sid
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Similars
Article
PubMed
n/an/a 580n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...

Bioorg Med Chem Lett 21: 5684-7 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.038
BindingDB Entry DOI: 10.7270/Q2TB179T
More data for this
Ligand-Target Pair