BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Vitamin D3 receptor' and Ligand = 'BDBM50329707'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50329707 ((S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Binding affinity to VDR receptor				Bioorg Med Chem Lett 20: 6661-6 (2010) Article DOI: 10.1016/j.bmcl.2010.09.011 BindingDB Entry DOI: 10.7270/Q20K29J4
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50329707 ((S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.66	n/a	n/a	n/a	n/a
National Institute of Health Sciences Curated by ChEMBL					Assay Description Effect on VDR transcriptional activity in human osteosarcoma cells				Bioorg Med Chem Lett 18: 120-3 (2008) Article DOI: 10.1016/j.bmcl.2007.11.007 BindingDB Entry DOI: 10.7270/Q2Q2414J
National Institute of Health Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50329707 ((S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	21.1	n/a	n/a	n/a	n/a
National Institute of Health Sciences Curated by ChEMBL					Assay Description Effect on VDR transcriptional activity in human Caco-2 cells in presence of 5% fetal calf serum				Bioorg Med Chem Lett 18: 120-3 (2008) Article DOI: 10.1016/j.bmcl.2007.11.007 BindingDB Entry DOI: 10.7270/Q2Q2414J
National Institute of Health Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50329707 ((S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Vitamin-D activity at VDR receptor in human HL60 cells assessed as induction of cell differentiation by NBT reduction assay				Bioorg Med Chem Lett 20: 6661-6 (2010) Article DOI: 10.1016/j.bmcl.2010.09.011 BindingDB Entry DOI: 10.7270/Q20K29J4
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50329707 ((S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.90	n/a	n/a	n/a	n/a
National Institute of Health Sciences Curated by ChEMBL					Assay Description Effect on VDR transcriptional activity in human osteosarcoma cells in presence of 5% fetal calf serum				Bioorg Med Chem Lett 18: 120-3 (2008) Article DOI: 10.1016/j.bmcl.2007.11.007 BindingDB Entry DOI: 10.7270/Q2Q2414J
National Institute of Health Sciences Curated by ChEMBL					More data for this Ligand-Target Pair