Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vitamin K-dependent protein C' and Ligand = 'BDBM50140407'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vitamin K-dependent protein C (Homo sapiens (Human))	BDBM50140407 (2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES CN(C)C(=N)c1ccc(NC(=O)c2cc(C)nn2-c2cc3ccccc3cc2F)c(F)c1 Show InChI InChI=1S/C24H21F2N5O/c1-14-10-22(24(32)28-20-9-8-17(12-18(20)25)23(27)30(2)3)31(29-14)21-13-16-7-5-4-6-15(16)11-19(21)26/h4-13,27H,1-3H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound against activated protein C was determined				Bioorg Med Chem Lett 14: 1229-34 (2004) Article DOI: 10.1016/j.bmcl.2003.12.054 BindingDB Entry DOI: 10.7270/Q2QN6664
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