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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vitamin K-dependent protein C' and Ligand = 'BDBM50193244'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vitamin K-dependent protein C


(Homo sapiens (Human))
BDBM50193244
PNG
(CHEMBL378083 | {1-[2-(4-carbamimidoyl-benzylcarbam...)
Show SMILES NC(=N)c1ccc(CNC(=O)C2(Cc3ccccc3C2)NC(=O)C2(CCCC2)NCC(O)=O)cc1
Show InChI InChI=1S/C26H31N5O4/c27-22(28)18-9-7-17(8-10-18)15-29-23(34)26(13-19-5-1-2-6-20(19)14-26)31-24(35)25(11-3-4-12-25)30-16-21(32)33/h1-2,5-10,30H,3-4,11-16H2,(H3,27,28)(H,29,34)(H,31,35)(H,32,33)
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PC cid
PC sid
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Article
PubMed
n/an/a 5.30E+4n/an/an/an/an/an/a



Institut de Recherches Servier

Curated by ChEMBL


Assay Description
Inhibition of human aPC


J Med Chem 49: 5047-50 (2006)


Article DOI: 10.1021/jm0606950
BindingDB Entry DOI: 10.7270/Q2H994VN
More data for this
Ligand-Target Pair