BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Vitamin K-dependent protein C' and Ligand = 'BDBM50447527'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vitamin K-dependent protein C (Homo sapiens (Human))	BDBM50447527 (CHEMBL3115905) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Competitive inhibition of human APC using S-2366 as substrate				Bioorg Med Chem Lett 24: 821-7 (2014) Article DOI: 10.1016/j.bmcl.2013.12.094 BindingDB Entry DOI: 10.7270/Q2542Q3B
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin K-dependent protein C (Homo sapiens (Human))	BDBM50447527 (CHEMBL3115905) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...				Bioorg Med Chem Lett 24: 821-7 (2014) Article DOI: 10.1016/j.bmcl.2013.12.094 BindingDB Entry DOI: 10.7270/Q2542Q3B
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair