Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1S' and Ligand = 'BDBM50229275'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50229275 (CHEMBL74461) Show SMILES CCO\C(O)=C1\C(C(C(=O)OCC)=C(C)N=C1CSc1ccccc1C)c1ccccc1C(F)(F)F |c:15,t:12| Show InChI InChI=1S/C27H28F3NO4S/c1-5-34-25(32)22-17(4)31-20(15-36-21-14-10-7-11-16(21)3)24(26(33)35-6-2)23(22)18-12-8-9-13-19(18)27(28,29)30/h7-14,23,33H,5-6,15H2,1-4H3/b26-24+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Affinity to bind dihydropyridine receptor (DHP receptor) by inhibiting the radioligand [3H]nitrendipine				J Med Chem 34: 2248-60 (1991) BindingDB Entry DOI: 10.7270/Q27P91MK
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