Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1S' and Ligand = 'BDBM50229281'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50229281 (CHEMBL74405) Show SMILES CCO\C(O)=C1\C(C(C#N)=C(C)N=C1CSc1ccc(Cl)c(Cl)c1)c1ccccc1C(F)(F)F |c:12,t:9| Show InChI InChI=1S/C24H19Cl2F3N2O2S/c1-3-33-23(32)22-20(12-34-14-8-9-18(25)19(26)10-14)31-13(2)16(11-30)21(22)15-6-4-5-7-17(15)24(27,28)29/h4-10,21,32H,3,12H2,1-2H3/b23-22+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Affinity to bind dihydropyridine receptor (DHP receptor) by inhibiting the radioligand [3H]nitrendipine				J Med Chem 34: 2248-60 (1991) BindingDB Entry DOI: 10.7270/Q27P91MK
					More data for this Ligand-Target Pair