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Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent T-type calcium channel subunit alpha-1H' and Ligand = 'BDBM363976'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))		BDBM363976
PNG
(N-[(exo)-8-(tert-Butylcarbamoyl)methyl-8-azabicycl...)
Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)c1coc3ccccc13)C2 |r,THB:7:8:13.14.28:10.11|
Show InChI InChI=1S/C23H31N3O3/c1-23(2,3)25-21(27)13-26-16-8-9-17(26)11-15(10-16)12-24-22(28)19-14-29-20-7-5-4-6-18(19)20/h4-7,14-17H,8-13H2,1-3H3,(H,24,28)(H,25,27)/t15-,16-,17+
UniProtKB/SwissProt

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n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company



Assay Description
The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...

J Med Chem 49: 2440-55 (2006)


BindingDB Entry DOI: 10.7270/Q2G73H2M
More data for this
Ligand-Target Pair