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Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent T-type calcium channel subunit alpha-1H' and Ligand = 'BDBM50192660'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))		BDBM50192660
PNG
(CHEMBL3923714)
Show SMILES CC(C)NC(=O)N1N=C(CC1c1ccc(F)cc1)c1ccc(Br)cc1 |c:7|
Show InChI InChI=1S/C19H19BrFN3O/c1-12(2)22-19(25)24-18(14-5-9-16(21)10-6-14)11-17(23-24)13-3-7-15(20)8-4-13/h3-10,12,18H,11H2,1-2H3,(H,22,25)
UniProtKB/SwissProt

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Article
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Actelion Pharmaceuticals Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human T-type calcium channel Cav3.2 expressed in CHO cells assessed as inhibition of calcium tail current at -90 mV holding potential m...

J Med Chem 59: 8398-411 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00756
BindingDB Entry DOI: 10.7270/Q2J67JWK
More data for this
Ligand-Target Pair