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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent T-type calcium channel subunit alpha-1H' and Ligand = 'BDBM50200874'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))		BDBM50200874
PNG
(CHEMBL3979902)
Show SMILES C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)C1CCOCC1 |r|
Show InChI InChI=1S/C24H30N2O2/c1-18-16-25(17-20-8-4-3-5-9-20)23-11-7-6-10-22(23)19(2)26(18)24(27)21-12-14-28-15-13-21/h3-11,18-19,21H,12-17H2,1-2H3/t18-,19+/m1/s1
UniProtKB/SwissProt

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Article
PubMed
n/an/a 47n/an/an/an/an/an/a



Actelion Pharmaceuticals Ltd.

Curated by ChEMBL


Assay Description
Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...

J Med Chem 59: 10661-10675 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01356
BindingDB Entry DOI: 10.7270/Q2RV0QN8
More data for this
Ligand-Target Pair