Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Voltage-dependent T-type calcium channel subunit alpha-1H' and Ligand = 'BDBM50322941'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322941 (2-(3-chlorophenyl)-N-(3,4-difluorophenyl)-1-oxo-3-...) Show SMILES Fc1ccc(NC(=O)N2CCC3(CC2)C(N(C3=O)c2cccc(Cl)c2)c2ccccn2)cc1F Show InChI InChI=1S/C25H21ClF2N4O2/c26-16-4-3-5-18(14-16)32-22(21-6-1-2-11-29-21)25(23(32)33)9-12-31(13-10-25)24(34)30-17-7-8-19(27)20(28)15-17/h1-8,11,14-15,22H,9-10,12-13H2,(H,30,34)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assay				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322941 (2-(3-chlorophenyl)-N-(3,4-difluorophenyl)-1-oxo-3-...) Show SMILES Fc1ccc(NC(=O)N2CCC3(CC2)C(N(C3=O)c2cccc(Cl)c2)c2ccccn2)cc1F Show InChI InChI=1S/C25H21ClF2N4O2/c26-16-4-3-5-18(14-16)32-22(21-6-1-2-11-29-21)25(23(32)33)9-12-31(13-10-25)24(34)30-17-7-8-19(27)20(28)15-17/h1-8,11,14-15,22H,9-10,12-13H2,(H,30,34)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assay				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322941 (2-(3-chlorophenyl)-N-(3,4-difluorophenyl)-1-oxo-3-...) Show SMILES Fc1ccc(NC(=O)N2CCC3(CC2)C(N(C3=O)c2cccc(Cl)c2)c2ccccn2)cc1F Show InChI InChI=1S/C25H21ClF2N4O2/c26-16-4-3-5-18(14-16)32-22(21-6-1-2-11-29-21)25(23(32)33)9-12-31(13-10-25)24(34)30-17-7-8-19(27)20(28)15-17/h1-8,11,14-15,22H,9-10,12-13H2,(H,30,34)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp method				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair