Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Voltage-dependent T-type calcium channel subunit alpha-1H' and Ligand = 'BDBM50322949'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322949 (2-(3-chloro-4-fluorophenyl)-7-(6-chloro-5-fluoro-1...) Show SMILES Fc1ccc(cc1Cl)N1C(c2ccccn2)C2(CCN(CC2)c2nc3cc(Cl)c(F)cc3[nH]2)C1=O Show InChI InChI=1S/C25H19Cl2F2N5O/c26-15-11-14(4-5-17(15)28)34-22(19-3-1-2-8-30-19)25(23(34)35)6-9-33(10-7-25)24-31-20-12-16(27)18(29)13-21(20)32-24/h1-5,8,11-13,22H,6-7,9-10H2,(H,31,32)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assay				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50322949 (2-(3-chloro-4-fluorophenyl)-7-(6-chloro-5-fluoro-1...) Show SMILES Fc1ccc(cc1Cl)N1C(c2ccccn2)C2(CCN(CC2)c2nc3cc(Cl)c(F)cc3[nH]2)C1=O Show InChI InChI=1S/C25H19Cl2F2N5O/c26-15-11-14(4-5-17(15)28)34-22(19-3-1-2-8-30-19)25(23(34)35)6-9-33(10-7-25)24-31-20-12-16(27)18(29)13-21(20)32-24/h1-5,8,11-13,22H,6-7,9-10H2,(H,31,32)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp method				Bioorg Med Chem Lett 20: 4602-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.012 BindingDB Entry DOI: 10.7270/Q2NS0V34
					More data for this Ligand-Target Pair