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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent calcium channel gamma-2 subunit' and Ligand = 'BDBM292053'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent calcium channel gamma-2 subunit


(Homo sapiens (Human))		BDBM292053
PNG
(3-(7-Chloro-1H-indazol-5-yl)-2-isopropyl-5-(triflu...)
Show SMILES CC(C)n1nc2ccc(nc2c1-c1cc(Cl)c2[nH]ncc2c1)C(F)(F)F
Show InChI InChI=1S/C17H13ClF3N5/c1-8(2)26-16(9-5-10-7-22-24-14(10)11(18)6-9)15-12(25-26)3-4-13(23-15)17(19,20)21/h3-8H,1-2H3,(H,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0630n/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...

US Patent US10100045 (2018)


BindingDB Entry DOI: 10.7270/Q2MW2K56
More data for this
Ligand-Target Pair