Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent calcium channel gamma-2 subunit' and Ligand = 'BDBM292061'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel gamma-2 subunit (Homo sapiens (Human))	BDBM292061 (5-(Difluoromethyl)-2-isopropyl-3-(7-methyl-1H-inda...) Show SMILES CC(C)n1nc2ccc(nc2c1-c1cc(C)c2[nH]ncc2c1)C(F)F Show InChI InChI=1S/C18H17F2N5/c1-9(2)25-17(11-6-10(3)15-12(7-11)8-21-23-15)16-13(24-25)4-5-14(22-16)18(19)20/h4-9,18H,1-3H3,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...				US Patent US10100045 (2018) BindingDB Entry DOI: 10.7270/Q2MW2K56
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