Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent calcium channel gamma-8 subunit' and Ligand = 'BDBM288237'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel gamma-8 subunit (Homo sapiens (Human))	BDBM288237 (6-(4-Fluorophenyl)-5-(7-methyl-1H-indazol-5-yl)-2-...) Show SMILES Cc1cc(cc2cn[nH]c12)-c1c(ccc2nc(nn12)C(F)(F)F)-c1ccc(F)cc1 Show InChI InChI=1S/C21H13F4N5/c1-11-8-13(9-14-10-26-28-18(11)14)19-16(12-2-4-15(22)5-3-12)6-7-17-27-20(21(23,24)25)29-30(17)19/h2-10H,1H3,(H,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...				US Patent US10087185 (2018) BindingDB Entry DOI: 10.7270/Q2QZ2D0H
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