Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent calcium channel gamma-8 subunit' and Ligand = 'BDBM288294'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel gamma-8 subunit (Homo sapiens (Human))	BDBM288294 (5-(7-Chloro-1H-indazol-5-yl)-2-cyclopropyl-6-(difl...) Show SMILES Cc1cc(C(F)F)c(-c2cc(Cl)c3[nH]ncc3c2)n2nc(nc12)C1CC1 Show InChI InChI=1S/C18H14ClF2N5/c1-8-4-12(16(20)21)15(26-18(8)23-17(25-26)9-2-3-9)10-5-11-7-22-24-14(11)13(19)6-10/h4-7,9,16H,2-3H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...				US Patent US10087185 (2018) BindingDB Entry DOI: 10.7270/Q2QZ2D0H
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