Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent calcium channel gamma-8 subunit' and Ligand = 'BDBM288304'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel gamma-8 subunit (Homo sapiens (Human))	BDBM288304 (5-[6-(Difluoromethyl)-4-methyl-2-(trifluoromethyl)...) Show SMILES Cc1cc(cc2CC(=O)Nc12)-c1c(cc(C)c2cc(nn12)C(F)(F)F)C(F)F Show InChI InChI=1S/C19H14F5N3O/c1-8-4-12(18(20)21)17(27-13(8)7-14(26-27)19(22,23)24)11-3-9(2)16-10(5-11)6-15(28)25-16/h3-5,7,18H,6H2,1-2H3,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...				US Patent US10087185 (2018) BindingDB Entry DOI: 10.7270/Q2QZ2D0H
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