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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Voltage-gated T-type calcium channel' and Ligand = 'BDBM50262085'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated T-type calcium channel


(Homo sapiens (Human))
BDBM50262085
PNG
(CHEMBL468397 | methyl 5-((3-(1H-benzo[d]imidazol-2...)
Show SMILES COC(=O)C(CCCN(C)CCCc1nc2ccccc2[nH]1)(C(C)C)c1ccc(Br)cc1
Show InChI InChI=1S/C26H34BrN3O2/c1-19(2)26(25(31)32-4,20-12-14-21(27)15-13-20)16-8-18-30(3)17-7-11-24-28-22-9-5-6-10-23(22)29-24/h5-6,9-10,12-15,19H,7-8,11,16-18H2,1-4H3,(H,28,29)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.17n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents at 1 uM by w...


Bioorg Med Chem Lett 18: 4424-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.037
BindingDB Entry DOI: 10.7270/Q2TT4QRD
More data for this
Ligand-Target Pair
Voltage-gated T-type calcium channel


(Homo sapiens (Human))
BDBM50262085
PNG
(CHEMBL468397 | methyl 5-((3-(1H-benzo[d]imidazol-2...)
Show SMILES COC(=O)C(CCCN(C)CCCc1nc2ccccc2[nH]1)(C(C)C)c1ccc(Br)cc1
Show InChI InChI=1S/C26H34BrN3O2/c1-19(2)26(25(31)32-4,20-12-14-21(27)15-13-20)16-8-18-30(3)17-7-11-24-28-22-9-5-6-10-23(22)29-24/h5-6,9-10,12-15,19H,7-8,11,16-18H2,1-4H3,(H,28,29)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.17n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel...


Bioorg Med Chem Lett 18: 4424-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.037
BindingDB Entry DOI: 10.7270/Q2TT4QRD
More data for this
Ligand-Target Pair