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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-gated potassium channel subunit Kv2.1 (Kv2.1)' and Ligand = 'BDBM50088573'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv2.1 (Kv2.1)


(Homo sapiens (Human))
BDBM50088573
PNG
(CHEMBL3577208)
Show SMILES COc1cccc(OC)c1C(=O)c1c(O)cc(C)c(OC)c1C1=C(c2c(C1=O)c(OC)c(C)cc2O)c1c(OC)cccc1OC |t:24|
Show InChI InChI=1S/C36H34O10/c1-17-16-20(38)26(33(39)28-23(43-5)13-10-14-24(28)44-6)31(35(17)45-7)30-29(27-21(41-3)11-9-12-22(27)42-4)25-19(37)15-18(2)36(46-8)32(25)34(30)40/h9-16,37-38H,1-8H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 590n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of Kv2.1 channel in human INS1 cells assessed as inhibition of outward K+ current by electrophysiology/patch clamp technique


J Nat Prod 78: 363-7 (2015)


Article DOI: 10.1021/np5007586
BindingDB Entry DOI: 10.7270/Q20P11R5
More data for this
Ligand-Target Pair