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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'alpha-Glucosidase (alpha-Glu)' and Ligand = 'BDBM223122'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223122
PNG
((Z)-N'-(5-chloro-1-(3-fluorobenzyl)-2-oxoindol...)
Show SMILES Fc1cccc(CN2C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c3cc(Cl)ccc23)c1
Show InChI InChI=1S/C26H17ClFN3O5/c27-17-6-8-21-20(11-17)25(26(34)31(21)13-15-2-1-3-18(28)10-15)30-29-23(32)14-35-19-7-4-16-5-9-24(33)36-22(16)12-19/h1-12H,13-14H2,(H,29,32)/b30-25-
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KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.88E+3n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair