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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'alpha-Glucosidase (alpha-Glu)' and Ligand = 'BDBM223125'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223125
PNG
((Z)-N'-(5-bromo-1-(4-bromobenzyl)-2-oxoindolin...)
Show SMILES Brc1ccc(CN2C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c3cc(Br)ccc23)cc1
Show InChI InChI=1S/C26H17Br2N3O5/c27-17-5-1-15(2-6-17)13-31-21-9-7-18(28)11-20(21)25(26(31)34)30-29-23(32)14-35-19-8-3-16-4-10-24(33)36-22(16)12-19/h1-12H,13-14H2,(H,29,32)/b30-25-
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KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.98E+3n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair