Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM125557'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM125557 (US8772316, 40) Show SMILES CCNc1nc2ccc(OC)cc2cc1Cc1c2cc(OC)c(OC)cc2c(CC)[nH]c1=O Show InChI InChI=1S/C26H29N3O4/c1-6-21-19-14-24(33-5)23(32-4)13-18(19)20(26(30)29-21)12-16-10-15-11-17(31-3)8-9-22(15)28-25(16)27-7-2/h8-11,13-14H,6-7,12H2,1-5H3,(H,27,28)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc.; Exonhit Therapeutics SA US Patent					Assay Description The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...				US Patent US8772316 (2014) BindingDB Entry DOI: 10.7270/Q2Q81BR8
					More data for this Ligand-Target Pair