Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM125558'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM125558 (US8772316, 41) Show SMILES CCNc1nc2ccc(OCC)cc2cc1Cc1c2cc(OC)c(OC)cc2c(CC)[nH]c1=O Show InChI InChI=1S/C27H31N3O4/c1-6-22-20-15-25(33-5)24(32-4)14-19(20)21(27(31)30-22)13-17-11-16-12-18(34-8-3)9-10-23(16)29-26(17)28-7-2/h9-12,14-15H,6-8,13H2,1-5H3,(H,28,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc.; Exonhit Therapeutics SA US Patent					Assay Description The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...				US Patent US8772316 (2014) BindingDB Entry DOI: 10.7270/Q2Q81BR8
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