Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM125566'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM125566 (US8772316, 49) Show SMILES CCCc1[nH]c(=O)c(Cc2cc3cc(OCC)ccc3nc2NCC)c2cc(OC)c(OC)cc12 Show InChI InChI=1S/C28H33N3O4/c1-6-9-24-21-16-26(34-5)25(33-4)15-20(21)22(28(32)31-24)14-18-12-17-13-19(35-8-3)10-11-23(17)30-27(18)29-7-2/h10-13,15-16H,6-9,14H2,1-5H3,(H,29,30)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc.; Exonhit Therapeutics SA US Patent					Assay Description The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...				US Patent US8772316 (2014) BindingDB Entry DOI: 10.7270/Q2Q81BR8
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