Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM163733'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM163733 (US9062059, 3-13) Show SMILES COc1ccc(nc1)[C@H]1C[C@@H]1COc1nc(N)nc(NCc2nnc(C)s2)c1F |r| Show InChI InChI=1S/C18H20FN7O2S/c1-9-25-26-14(29-9)7-22-16-15(19)17(24-18(20)23-16)28-8-10-5-12(10)13-4-3-11(27-2)6-21-13/h3-4,6,10,12H,5,7-8H2,1-2H3,(H3,20,22,23,24)/t10-,12+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description PDE10A2 was amplified from human fetal brain cDNA (Clontech, Mountain View, Calif.) using a forward primer corresponding to nucleotides 56-77 of huma...				US Patent US9062059 (2015) BindingDB Entry DOI: 10.7270/Q29022J5
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