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Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM304034'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM304034
PNG
(5,7-Dimethyl-2-[3-(pyridin-4-yl)-1H-benzimidazol-5...)
Show SMILES Cc1cc(C)n2nc(nc2n1)-c1ccc2[nH]c(nc2c1)-c1ccncc1
Show InChI InChI=1S/C19H15N7/c1-11-9-12(2)26-19(21-11)24-18(25-26)14-3-4-15-16(10-14)23-17(22-15)13-5-7-20-8-6-13/h3-10H,1-2H3,(H,22,23)
PDB
MMDB

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PC cid
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US Patent
n/an/a 953n/an/an/an/an/an/a



CELON PHARMA S.A.

US Patent


Assay Description
Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...


US Patent US10138245 (2018)


BindingDB Entry DOI: 10.7270/Q2M32XTX
More data for this
Ligand-Target Pair