Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM304042'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM304042 (US10138245, Example 56) Show SMILES Cc1cc(C)n2nc(nc2n1)-c1ccn2cc(nc2n1)-c1ccccc1 Show InChI InChI=1S/C19H15N7/c1-12-10-13(2)26-19(20-12)23-17(24-26)15-8-9-25-11-16(22-18(25)21-15)14-6-4-3-5-7-14/h3-11H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Celon Pharma S.A. Curated by ChEMBL					Assay Description Inhibition of Ca2+/calmodulin-induced recombinant human full length N-terminal GST-tagged PDE10A1 expressed in baculovirus infected Sf9 cells using c...				Eur J Med Chem 155: 96-116 (2018) Article DOI: 10.1016/j.ejmech.2018.05.043 BindingDB Entry DOI: 10.7270/Q2ZP48P0
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM304042 (US10138245, Example 56) Show SMILES Cc1cc(C)n2nc(nc2n1)-c1ccn2cc(nc2n1)-c1ccccc1 Show InChI InChI=1S/C19H15N7/c1-12-10-13(2)26-19(20-12)23-17(24-26)15-8-9-25-11-16(22-18(25)21-15)14-6-4-3-5-7-14/h3-11H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
CELON PHARMA S.A. US Patent					Assay Description Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...				US Patent US10138245 (2018) BindingDB Entry DOI: 10.7270/Q2M32XTX
					More data for this Ligand-Target Pair