Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM329523'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM329523 (2-((1S,2S)-2-((5- (imidazo[1,2-a]pyridin-6- yl)-2-...) Show SMILES Cc1ncc(-c2ccc3nccn3c2)c(OC[C@H]2C[C@@H]2c2ccc3ccccc3n2)n1 |r| Show InChI InChI=1S/C25H21N5O/c1-16-27-13-21(18-7-9-24-26-10-11-30(24)14-18)25(28-16)31-15-19-12-20(19)23-8-6-17-4-2-3-5-22(17)29-23/h2-11,13-14,19-20H,12,15H2,1H3/t19-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...				US Patent US9663513 (2017) BindingDB Entry DOI: 10.7270/Q25D8TXC
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