Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50209516'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50209516 (4-[3-cyano-2-(2'-ethoxy-2-methyl-biphenyl-4-yl)-6-...) Show SMILES CCOc1ccccc1-c1ccc(cc1C)-c1nc2ccc(F)cc2c(NCCCC(O)=O)c1C#N Show InChI InChI=1S/C29H26FN3O3/c1-3-36-26-8-5-4-7-22(26)21-12-10-19(15-18(21)2)28-24(17-31)29(32-14-6-9-27(34)35)23-16-20(30)11-13-25(23)33-28/h4-5,7-8,10-13,15-16H,3,6,9,14H2,1-2H3,(H,32,33)(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE10A transfected in insect Sf9 cells by scintillation proximity assay				Bioorg Med Chem Lett 17: 2869-73 (2007) Article DOI: 10.1016/j.bmcl.2007.02.061 BindingDB Entry DOI: 10.7270/Q2NS0TK0
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