Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50209533'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50209533 ((R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-7-methy...) Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2cc(C)ccc2c(N[C@H](C)C(O)=O)c1C#N Show InChI InChI=1S/C28H25N3O3/c1-4-34-25-8-6-5-7-21(25)19-10-12-20(13-11-19)26-23(16-29)27(30-18(3)28(32)33)22-14-9-17(2)15-24(22)31-26/h5-15,18H,4H2,1-3H3,(H,30,31)(H,32,33)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE10A transfected in insect Sf9 cells by scintillation proximity assay				Bioorg Med Chem Lett 17: 2869-73 (2007) Article DOI: 10.1016/j.bmcl.2007.02.061 BindingDB Entry DOI: 10.7270/Q2NS0TK0
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