Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50334652'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50334652 (3-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)p...) Show SMILES Cn1cc(c(n1)-c1ccc(OCc2cc3ccccc3cn2)cc1)-c1ccncc1 Show InChI InChI=1S/C25H20N4O/c1-29-16-24(18-10-12-26-13-11-18)25(28-29)19-6-8-23(9-7-19)30-17-22-14-20-4-2-3-5-21(20)15-27-22/h2-16H,17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Sassari Curated by ChEMBL					Assay Description Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assay				Bioorg Med Chem 19: 642-9 (2011) Article DOI: 10.1016/j.bmc.2010.10.038 BindingDB Entry DOI: 10.7270/Q2TT4R73
					More data for this Ligand-Target Pair